Established in 1733, St George's has claim to be the oldest medical school in England.

The current structure of Barts medical school was formed by the 1785 merger of the Medical College of St Bartholomew's Hospital (founded 1123) and the London Hospital Medical College. It has claim to be the oldest and first medical school in England and Wales. St Bartholomew’s Hospital Medical College and The London Hospital Medical College merged In 1995 with Queen Mary University.

The medical school was established in 1824. Previously, medical teaching began in 1752, when Charles White founded the Manchester Royal Infirmary as the first modern hospital in the Manchester area.

In 1828 Arnold James Knight and Hall Overend made motions to found a public medical school in Sheffield, and the new medical school was formally opened as the Sheffield Medical Institution in July 1829. In 1905, the university college received its royal charter to become the University of Sheffield and Medicine was a founding faculty at the university.

Bristol Medical School was originally established in 1833, and later became amalgamated with University College, Bristol in 1893.

A medical school in Liverpool was originally established in 1834. This became attached in 1844 to the Liverpool Infirmary and was renamed in 1851 as the Liverpool Royal Infirmary School of Medicine.  From 1881 it operated as University College Liverpool.  The school used to have a problem-based learning (PBL) curriculum, which was replaced in 2014 with a new 'integrated' curriculum for its five-year MBChB course.

Originally founded in 1893, and previously known as the Welsh National School of Medicine and the University of Wales College of Medicine, this medical school was re-amalgamated into Cardiff University in 2004.

The current structure of the medical school at Oxford was established in 1946. Previously, medicine was taught here through various periods since the 13th century but was dormant during the 19th century.

Established in 1970, this school was formed following the 1968 recommendations of the Royal Commission on Medical Educationreport, popularly known as the Todd Report, that new medical schools should be established at the Universities of Nottingham, Leicester and Southampton. Its first cohort of 48 students graduated in 1975.

Established in 1975, this school was formed following the 1968 recommendations of the Royal Commission on Medical Educationreport, popularly known as the Todd Report, that new medical schools should be established at the Universities of Nottingham, Leicester and Southampton.

Imperial College London Medical School was established in 1997 by the merger of St Mary's Hospital Medical School, the National Heart and Lung Institute, the Royal Postgraduate Medical School and the Charing Cross and Westminster Medical School.

UCL medical school was established in 1998.  Previously, teaching of medicine was based elsewhere and the current structure of UCL medical school derives from several mergers:  in 1987, a merger between the medical schools of Middlesex Hospital (1746) and University College Hospital (1834), and a subsequent merger in 1998 with the Royal Free Hospital School of Medicine (founded as the London School of Medicine for Women in 1874).

This  medical school, based at the University of East Anglia, in Norwich, was previously called University of East Anglia School of Medicine Health Policy and Practice. The first cohort of 110 students was in 2002.

This medical school began teaching undergraduate clinical medicine in 2003, using the Manchester curriculum, with the MBChB degree  awarded by the University of Manchester until 2011. From 2012 (2007 intake) the MBChB degree was awarded by Keele University itself.

Established in 2013, after the split of the Peninsula College of Medicine and Dentistry (founded 2000).

Exeter Medical School was established in 2013 after the split of the Peninsula College of Medicine and Dentistry (founded 2000).

Originally planned as an independent private medical school, mainly for international students, Aston since 2018 has received Government funding for Home / UK students. The first undergraduate MBChB students commenced studies in September 2018, following approval of its programme by the UK General Medical Council. In 2019, 'Widening Access' students were allocated 40% of places.

Lincoln is a new medical school, where the first student cohort commenced studies in 2019.

This new medical school, established in 2020, is a collaboration between the University of Kent and Canterbury Christchurch University. This medical school allocates 100 places each year, with up to 8 international, and its partner medical school is Brighton.